A large international study has probed the causes of lupus-related psychosis—a serious condition marked by delusions and hallucinations. Dr. John Hanly and his co-authors at research centers across several continents found that lupus psychosis (LP) is quite rare, affecting only 1.5 percent of people with lupus. They also observed that the condition tends to occur more often in the first few years after a diagnosis with lupus and is more frequent among male patients and patients of African descent.